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Gran Área: Ciencias médicas y de la salud
Área: Medicina clínica
Subárea: Oncología

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Resultado: 333 registro(s)

16866

Autophagy

Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging Vol. 3

 

Academic Press, 2014.

ISBNs 9780124055292

Colección: ScienceDirect

Resumen (en inglés):

Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and up-to-date, this book offers a valuable guide to these cellular processes whilst encouraging researchers to explore their potentially important connections.

Volume 3 explores the role of autophagy in specific diseases and developments, including: Crohn’s Disease, Gaucher Disease, Huntington’s Disease, HCV infection, osteoarthritis, and liver injury. A full section is devoted to in-depth exploration of autophagy in tumor development and cancer. Finally, the work explores the relationship between autophagy and apoptosis, with attention to the ways in which autophagy regulates apoptosis, and the ways in which autophagy has been explored in Lepidoptera, elucidating the use of larval midgut as a model for such exploration.  From these well-developed foundations, researchers, translational scientists, and practitioners may work to better implement more effective therapies against some of the most devastating human diseases.

Volumes in the Series

Volume 1: Molecular Mechanisms. Elucidates autophagy’s association with numerous biological processes, including cellular development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer’s, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Volume 2: Role in General Diseases. Describes the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general diseases.  Volume 3: Role in Specific Diseases. Explores the role of autophagy in specific diseases and developments, including: Crohn’s Disease, Gaucher Disease, Huntington’s Disease, HCV infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor development and cancer, as well as the relationship between autophagy and apoptosis. Volume 4: Mitophagy. Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson Disease, cardiac aging, and skeletal muscle atrophy. Volume 5: Role in Human Diseases. Comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer; and the duality of autophagy’s effects in various cardiovascular, metabolic, and neurodegenerative disorders. Volume 6: Regulation of Autophagy and Selective Autophagy. Provides coverage of the mechanisms of regulation of autophagy; intracellular pathogen use of the autophagy mechanism; the role of autophagy in host immunity; and selective autophagy. Volume 7: Role of Autophagy in Therapeutic Applications. Provides coverage of the latest developments in autophagosome biogenesis and regulation; the role of autophagy in protein quality control; the role of autophagy in apoptosis; autophagy in the cardiovascular system; and the relationships between autophagy and lifestyle.  Volume 8: Autophagy and Human Diseases. Reviews recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, and introduces new, more effective therapeutic strategies, in the development of targeted drugs and programmed cell death, providing information that will aid on preventing detrimental inflammation. Volume 9: Necrosis and Inflammation in Human Diseases. Emphasizes the role of Autophagy in necrosis and inflammation, explaining in detail the molecular mechanism(s) underlying the formation of autophagosomes, including the progression of Omegasomes to autophagosomes.

  • Brings together oncologists, neurosurgeons, physicians, research scientists, and pathologists in the field of autophagy to discuss cutting-edge developments in this rapidly-advancing field
  • Builds upon recent advances in genome-scale approaches and computational tools to discuss the advances in regulation of autophagy at the systems level
  • Organized for readers into easy-to-access sections: molecular mechanisms; role of autophagy in disease; role of autophagy in cancer; and autophagy and apoptosis
  • Explores exciting new developments, including the measurement of autophagic flux; the molecular role of the Atg12-Atg5-Atg16 complex; and the molecular bases of autophagosome formation in yeast


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8433

BIOELECTROMAGNETICS Current Concepts

The Mechanisms of the Biological Effect of Extremely High Power Pulses

 

13th ed. Dordrecht: Springer, 2006.

Título de la serie/colección: NATO Security Through Science Series.

ISBNs 9781402042768 9781402042782

Colección: SpringerLink


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9827

Biological Basis of Geriatric Oncology

Vol. 124

 

13th ed. Boston, MA: Springer Science+Business Media, 2005.

Título de la serie/colección: Cancer Treatment and Research. ISSN 0927-3042,

ISBNs 9780387239613 9780387239620

Colección: SpringerLink


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9856

Biologie und Epidemiologie der Hormonersatztherapie

Biology and Epidemiology of Hormone Replacement Therapy: Diskussionen zur Postmenopausalen Gesundheit: Discussions on Post-Menopausal Health Vol. 13

 

13th ed. Berlin, Heidelberg: Springer-Verlag GmbH, 2006.

Título de la serie/colección: Ernst Schering Research Foundation Workshop. ISSN 0947-6075,

ISBNs 9783540323419 9783540378617

Colección: SpringerLink


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23257

Biology-Driven Targeted Therapy of Pediatric Soft-Tissue and Bone Tumors

Current Opportunities and Future Challenges

 

Frontiers Media SA, 2016.

Título de la serie/colección: Frontiers Research Topics. ISSN 1664-8714,

ISBNs 9782889198191

Colección: Directory of Open Access Books


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17012

Biomaterials for Cancer Therapeutics

Diagnosis, Prevention and Therapy

 

Woodhead Publishing, 2014.

ISBNs 9780857096647

Colección: ScienceDirect

Resumen (en inglés): Cancer can affect people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is now being developed to target, treat and prevent cancer. This unique book discusses the role and potential of biomaterials in treating this prevalent disease.

The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Chapters in part two discuss synthetic vaccines, proteins and polymers for cancer therapeutics. Part three focusses on theranosis and drug delivery systems, whilst the final set of chapters look at biomaterial therapies and cancer cell interaction.

This extensive book provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer. Biomaterials for cancer therapeutics is an essential text for academics, scientists and researchers within the biomedical industry, and will also be of interest to clinicians with a research interest in cancer therapies and biomaterials.

  • A complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer
  • Discusses the fundamentals of biomaterials for cancer therapeutics
  • Discusses synthetic vaccines, proteins and polymers for cancer therapeutics


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22592

Blaue Buch, Das

Chemotherapie-Manual Hämatologie und Onkologie

 

Springer, 2016.

ISBNs 9783662514191 9783662514207

Colección: Directory of Open Access Books


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17073

Bone Cancer

Primary Bone Cancers and Bone Metastases

 

2nd ed. Academic Press, 2015.

ISBNs 9780124167216

Colección: ScienceDirect

Resumen (en inglés):

Bone Cancer, 2nd Edition comprehensively investigates key discoveries in the field of bone biology over the last five years that have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches. The Second Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with key chapters from the first edition, and offers numerous new chapters describing the new concepts of bone cancer biology and therapy, for both primary bone tumors as well as bone metastases. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases – from bench to bedside: development (cellular and molecular mechanisms), genomic and proteomic analyses, clinical analyses (histopathology, imaging, pain monitoring), as well as new therapeutic approaches and clinical trials for primary bone tumors and bone metastases.

  • Presents a comprehensive, translational source for all aspects of primary bone cancer and bone metastases in one reference work
  • Provides a common language for cancer researchers, bone biologists, oncologists, and radiologists to discuss bone tumors and how bone cancer metastases affects each major organ system
  • Offers insights to research clinicians (oncologists and radiologists) into understanding the molecular basis of bone cancer, leading to more well-informed diagnoses and treatment of tumors and metastases
  • Offers insights to bone biologists into how clinical observations and practices can feed back into the research cycle and, therefore, can contribute to the development of more targeted genomic and proteomic assays


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3458

Bone Marrow-Derived Progenitors

Vol. 180

 

13th ed. Berlin, Heidelberg: Springer-Verlag, 2007.

Título de la serie/colección: Handbook of Experimental Pharmacology. ISSN 0171-2004,

ISBNs 9783540689751 9783540689768

Colección: SpringerLink


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17084

Brain Metastases from Primary Tumors

Epidemiology, Biology, and Therapy

 

Academic Press, 2014.

ISBNs 9780128008966

Colección: ScienceDirect

Resumen (en inglés):

With an annual rate of more than 12 million global diagnoses and 7.6 million deaths, the societal and economic burden of cancer cannot be overstated. Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. This volume fills that gap, serving as the first reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types – lung, breast, and melanoma. Additionally, biological background as well as therapy for CNS metastases is addressed. Age and gender related trends are also discussed, as is the use of biomarkers for early detection.

    *The only comprehensive reference detailing the link between primary cancers and brain metastases

    *Aids the target audience in determining the incidence of brain metastases in patients with a primary cancer

    *Provided education about the potential use of biomarkers for early detection, diagnosis and prevention of the spread of primary cancer to the brain

    *Documents temporal and gender-related trends in brain metastases from other cancers

    *Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available


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