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Gran Área: Ingeniería, ciencia y tecnología
Área: Nanotecnología
Subárea: Nanomateriales

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Resultado: 15 registro(s)

5070

Nanotechnologies, Hazards and Resource Efficiency

A Three-Tiered Approach to Assessing the Implications of Nanotechnology and Influencing its Development

 

13th ed. Berlin, Heidelberg: Springer-Verlag, 2007.

ISBNs 9783540738824 9783540738152

Colección: SpringerLink


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5716

Nanotribology and Nanomechanics

An Introduction

 

13th ed. Berlin, Heidelberg: Springer-Verlag, 2005.

ISBNs 9783540242673 9783540282488

Colección: SpringerLink


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5622

Ordered Porous Nanostructures and Applications

 

13th ed. Boston, MA: Springer Science+Business Media, 2005.

Título de la serie/colección: Nanostructure Science and Technology. ISSN 1571-5744,

ISBNs 9780387235417 9780387251936

Colección: SpringerLink


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20242

Polymers and Nanomaterials for Gene Therapy

 

Woodhead Publishing, 2016.

ISBNs 9780081005200

Colección: ScienceDirect

Resumen (en inglés):

Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy.

The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy.

This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy.

  • Explores current challenges in the research of genetic diseases
  • Discusses polymers for gene therapy and their function in designing advanced materials
  • Provides examples of organic and inorganic nanomaterials for gene therapy
  • Includes labeling, targeting, and assays
  • Looks at characterization, physico-(bio)chemical properties, and applications


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1747

Understanding Carbon Nanotubes

From Basics to Applications Vol. 677

 

13th ed. Berlin, Heidelberg: Springer, 2006.

Título de la serie/colección: Lecture Notes in Physics. ISSN 0075-8450,

ISBNs 9783540269229 9783540375869

Colección: SpringerLink


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