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Gran Área: Ciencias médicas y de la salud
Área: Medicina básica
Subárea: Genética humana

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Resultado: 75 registro(s)

6167

Evolution and History of Human Populations in South Asia, The

Inter-disciplinary Studies in Archaeology, Biological Anthropology, Linguistics and Genetics

 

13th ed. Dordrecht: Springer, 2007.

Título de la serie/colección: Vertebrate Paleobiology and Paleoanthropology Series.

ISBNs 9781402055614 9781402055621

Colección: SpringerLink


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9587

Frontiers in Biochip Technology

 

13th ed. Boston, MA: Springer Science+Business Media, 2006.

ISBNs 9780387255682 9780387255859

Colección: SpringerLink


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9305

Fundamentals of Data Mining in Genomics and Proteomics

 

13th ed. Boston, MA: Springer Science+Business Media, 2007.

ISBNs 9780387475080 9780387475097

Colección: SpringerLink


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18431

Gene Therapy

Potential Applications of Nanotechnology

 

Woodhead Publishing, 2013.

ISBNs 9781907568404

Colección: ScienceDirect

Resumen (en inglés): Gene therapy is emerging as a new class of therapeutics for the treatment of inherited and acquired diseases. However, poor cellular uptake and instability of DNA in the physiological milieu limits its therapeutic potential, hence a vector which can protect and efficiently transport DNA to the target cells must be developed. Nanotechnology-based non-viral vectors have been proposed as potential candidates. Various polymeric nanoparticles have been shown to be suitable, with high cellular uptake efficiencies and reduced cytotoxicity. These delivery vectors form condensed complexes with DNA which result in shielding against enzymatic degradation and enhanced cellular targeting. Advantages including easy manipulatibility, high stability, low cost and high payload, mean that nanoparticles from various polymers have been exploited. Gene therapy gives a systematic account of the many aspects of nanotechnology mediated gene therapy, from the preparation of nanoparticles to physicochemical characterization, and follows with applications in in vitro and in vivo models. This book emphasizes the various aspects of nanotechnology-based gene therapy, with initial chapters detailing the tools and techniques available for preparation and in vitro and in vivo characterization of nanoparticles. Later chapters provide exhaustive details on polymeric systems employed for gene therapy.

  • Provides an overview of nanotechnology applications in gene therapy, from preparation of nanoparticles to in vitro and in vivo studies
  • Details the tools and techniques available for preparation, characterization and in vitro and in vivo study of nanoparticles
  • Details the limitations of nanoparticle-mediated gene therapy and proposes ways in which they may be overcome


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9258

Gene Therapy and Gene Delivery Systems

Vol. 99

 

13th ed. Berlin, Heidelberg: Springer-Verlag GmbH, 2005.

Título de la serie/colección: Advances in Biochemical Engineering/Biotechnology. ISSN 0724-6145,

ISBNs 9783540284048 9783540324126

Colección: SpringerLink


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8547

Gene Therapy of Autoimmune Diseases

 

13th ed. Boston, MA: Eurekah.com/Kluwer Academic/Plenum Publishers, 2005.

Título de la serie/colección: Medical Intelligence Unit.

ISBNs 9780306479915 9780387286709

Colección: SpringerLink


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3960

Genetic Control of Neuronal Migrations in Human Cortical Development

Vol. 189

 

13th ed. Berlin, Heidelberg: Springer-Verlag, 2007.

Título de la serie/colección: Advances in Anatomy, Embryology and Cell Biology. ISSN 0301-5556,

ISBNs 9783540366881 9783540366898

Colección: SpringerLink


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16

Genetic Engineering

Principles and Methods Vol. 27

 

13th ed. Boston, MA: Springer Science+Business Media, 2006.

Título de la serie/colección: Genetic Engineering: Principles and Methods. ISSN 1096-3716,

ISBNs 9780387258553 9780387258560

Colección: SpringerLink


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3620

Genetic Engineering

Principles and Methods

 

13th ed. Boston, MA: Springer Science+Business Media, 2007.

ISBNs 9780387338408 9780387345048

Colección: SpringerLink


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5235

Genome Exploitation

Data Mining the Genome

 

13th ed. Norwell: Springer Science+Business Media, 2005.

ISBNs 9780387241234 9780387241876

Colección: SpringerLink


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