MDPI AG - Multidisciplinary Digital Publishing Institute, 2015.
Título de la serie/colección:Processes. ISSN 2227-9717,
Colección: Directory of Open Access Books
Resumen (en inglés): This special issue contains the first papers of Processes and is intended to highlight a diverse set of topics related to process technology for the chemical, materials, biochemical, pharmaceutical and biomedical industries. To enhance the impact of these industries on society, process innovation that allows large-scale manufacturing is essential for both established and emerging technologies. The scope of this special issue includes, but is not limited to: chemical and biochemical reaction processes: mixing, fluid processing and heat transfer systems; mass transfer, separation and purification processes; integrated process design and scale-up; and process modeling, simulation, optimization and control. We are particularly interested in receiving manuscripts that integrate experimental and theoretical/computational studies as well as contributions from industry. We invite researchers and practitioners from all areas of process technology to submit manuscripts for this important special issue of Processes.
A. Cybulski, J. A. Moulijn, M. M. Sharma; R. A. Sheldon
Elsevier Science B.V., 2001.
Resumen (en inglés): The sector of fine chemicals, including pharmaceuticals, agrochemicals, dyes and pigments, fragrances and flavours, intermediates, and performance chemicals is growing fast. For obvious reasons chemistry is a key to the success in developing new processes for fine chemicals. However, as a rule, chemists formulate results of their work as recipes, which usually lack important information for process development. Fine Chemicals Manufacture, Technology and Engineering is intended to show what is needed to make the recipe more useful for process development purposes and to transform the recipe into an industrial process that will be safe, environmentally friendly, and profitable. The goal of this book is to form a bridge between chemists and specialists of all other branches involved in the scale-up of new processes or modification of existing processes with both a minimum effort and risk and maximum profit when commercializing the process. New techniques for scale-up and optimization of existing processes and improvements in the utilization of process equipment that have been developed in recent years are presented in the book.
Resumen (en inglés): A range of new and innovative tools used for preformulation and formulation of medicines help optimize pharmaceutical development projects. Such tools also assist with the performance evaluation of the pharmaceutical process, allowing any potential gaps to be identified. These tools can be applied in both basic research and industrial environment. Formulation tools for pharmaceutical development considers these key research and industrial tools.
Nine chapters by leading contributors cover: Artificial neural networks technology to model, understand, and optimize drug formulations; ME_expert 2.0: a heuristic decision support system for microemulsions formulation development; Expert system for the development and formulation of push-pull osmotic pump tablets containing poorly water-soluble drugs; SeDeM Diagram: an expert system for preformulation, characterization and optimization of tables obtained by direct compression; New SeDeM-ODT expert system: an expert system for formulation of orodispersible tablets obtained by direct compression; and 3D-cellular automata in computer-aided design of pharmaceutical formulations: mathematical concept and F-CAD software.
Coverage of artificial intelligence tools, new expert systems, understanding of pharmaceutical processes, robust development of medicines, and new ways to develop medicines
Development of drugs and medicines using mathematical tools
Compilation of expert system developed around the world
Funding of Biopharmaceutical Research and Development, The
D. R. Williams
Woodhead Publishing, 2013.
Resumen (en inglés): The funding of biopharmaceutical research and development provides a comprehensive critical review of the funding of research and development (R&D) in the human biopharmaceutical market sector. It addresses both private and public funding sources available in the US and internationally. The biopharmaceutical market is among the most research-intensive market sectors globally. Clinical researchers face a multitude of public and private funding options with respect to bringing their idea or innovation to market. These funding options are continually changing and complex, and are expected to decrease in the near future. A lack of understanding of the scale, scope, and inner workings of the funding aspects of R&D can, at times, act as a barrier for all involved, and can slow down or even eliminate the R&D process. The book lessens these barriers by describing the theoretical underpinnings, present practice, and trends in R&D funding in this market sector, both in the US and internationally. This includes a review and discussion of public-private partnership activity and their inner-workings, noting the complementary relationship between public and private funding. The book also contains an overview of the inner-workings of strategic alliance activity, including the advantages and disadvantages for each party. It goes on to provide an outline of venture capital activity, detailing the methods by which venture capital firms raise capital and are organized, a description of the venture capital-entrepreneur arrangement, and the effects of this arrangement. The book also presents an overview of the IPO process and the various fates of firms going public.
Presents a comprehensive view of the funding issues of R&D in this market sector, adopting a theory-to-practice approach
A comprehensive and analytical review of the biopharmaceutical R&D literature and practice
An overview of the various and competing/complementary theories of the firm and valuation methods as they apply to biopharmaceutical R&D