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Gran Área: Ciencias médicas y de la salud
Área: Medicina básica
Subárea: Farmacología y farmacia

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Resultado: 243 registro(s)

23924

Enabling Things to Talk

 

Springer, 2013.

ISBNs 9783642404023 9783642404030

Colección: Directory of Open Access Books


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17925

Encapsulation and Controlled Release

 

Woodhead Publishing, 1993.

ISBNs 9781855738201

Colección: ScienceDirect

Resumen (en inglés): Encapsulation and controlled release combines basic information on the subject with details of the latest research, making it suitable for both newcomers to the field and those with experience of encapsulation technology. It will also be of great interest to those working on water-soluble or dispersible polymers, as well as application chemists and biochemists in diverse areas.


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21238

Endocannabinoidome, The

The World of Endocannabinoids and Related Mediators

 

Academic Press, 2015.

ISBNs 9780124201262

Colección: ScienceDirect

Resumen (en inglés):

The Endocannabinoidome: The World of Endocannabinoids and Related Mediators is dedicated to the latest research and studies on endocannabinoids and cannabinoid receptors to illustrate their important role in the discovery of new, endocannabinoid-related, lipid mediators. Written by leading experts across different disciplines, this book focuses on the biochemical and anlayticial aspects of novel lipid signals, their pharmacological activities and their potential utilization for the development of new and effective therapeutic strategies. The first book of its kind, The Endocannabinoidome is a meaningful reference for all those involved in experimental efforts to further the development of this field.

  • Explores the novel and exciting aspects of several endocannabinoid-like molecules for which researchers are still seeking a function
  • Discusses the novel metabolic pathways for endocannabinoids in order to explain the failure of some clinical trials with inhibitors of more conventional metabolic pathways
  • Incorporates pharmacology, biochemistry and potential clinical applications to provide researchers with a complete look at endocannabinoids


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17929

Endocrine Disruption and Human Health

 

Academic Press, 2015.

ISBNs 9780128011393

Colección: ScienceDirect

Resumen (en inglés):

Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students.

  • Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health
  • Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health
  • Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations


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17966

Engineered Nanoparticles

Structure, Properties and Mechanisms of Toxicity

 

Academic Press, 2016.

ISBNs 9780128014066

Colección: ScienceDirect

Resumen (en inglés):

Engineered Nanoparticles: Structure, Properties and Mechanisms of Toxicity is an indispensable introduction to engineered nanomaterials (ENM) and their potential adverse effects on human health and the environment. Although research in the area of pharmacology and toxicology of ENM is rapidly advancing, a possible correlation between their physicochemical properties and biomedical properties or toxicity is not yet fully understood. This understanding is essential to develop strategies for the safe applications and handling of ENM.

The book comprehensively defines the current understanding of ENM toxicity, first describing these materials and their physicochemical properties, and then discussing the toxicological theory and methodology before finally demonstrating the potential impact of ENM on the environment and human health.

It represents an essential reference for students and investigators in toxicology, pharmacology, chemistry, material sciences, medicine, and those in related disciplines who require an introduction to ENM and their potential toxicological effects.

  • Provides state-of-the-art physicochemical descriptions and methodologies for the characterization of engineered nanomaterials (ENM)
  • Describes the potential toxicological effects of ENM and the nanotoxicological mechanisms of action
  • Presents how to apply theory to practice in a public health and risk assessment setting


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18019

Epi-Informatics

Discovery and Development of Small Molecule Epigenetic Drugs and Probes

 

Academic Press, 2016.

ISBNs 9780128028087

Colección: ScienceDirect

Resumen (en inglés):

Epi-Informatics: Discovery and Development of Small Molecule Epigenetic Drugs and Probes features multidisciplinary strategies with strong computational approaches that have led to the successful discovery and/or optimization of compounds that act as modulators of epigenetic targets. This book is intended for all those using or wanting to learn more about computational methodologies in epigenetic drug discovery, including molecular modelers, informaticians, pharmaceutical scientists, and medicinal chemists.

With a better understanding of different molecular modeling and cheminformatic approaches, readers can incorporate these techniques into their own drug discovery projects that may involve chemical synthesis and medium- or high-throughput screening. In addition, this book highlights the significance of epigenetic targets to the public health for molecular modelers and chemoinformatians. The goal of this reference is to stimulate ongoing multidisciplinary research and to further improve current computational methodologies and workflows in order to accelerate the discovery and development of epi-drugs and epi-probes.

  • Focuses on the discovery of epi-drugs as candidates to be used in therapy including combined therapies
  • Describes new computational methodologies and screening assays utilizing recent and emerging novel structural data
  • Highlights the discovery, development and optimization of epi-probes, which are molecular probes that elucidate epigenetic mechanisms
  • Includes important topics such as computational-guided optimization of epi-hits, virtual screening to identify novel compounds for epigenetic targets, development and mining of epigenetic molecular databases, SAR modeling of screening data and much more


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18049

Essential Chemistry for Formulators of Semisolid and Liquid Dosages

 

Academic Press, 2016.

ISBNs 9780128010242

Colección: ScienceDirect

Resumen (en inglés): A needed resource for pharmaceutical scientists and cosmetic chemists, Essential Chemistry for Formulators of Semisolid and Liquid Dosages provides insight into the basic chemistry of mixing different phases and test methods for the stability study of nonsolid formulations. The book covers foundational surface/colloid chemistry, which forms the necessary background for making emulsions, suspensions, solutions, and nano drug delivery systems, and the chemistry of mixing, which is critical for further formulation of drug delivery systems into semisolid (gels, creams, lotions, and ointments) or liquid final dosages. Expanding on these foundational principles, this useful guide explores stability testing methods, such as particle size, rheological/viscosity, microscopy, and chemical, and closes with a valuable discussion of regulatory issues. Essential Chemistry for Formulators of Semisolid and Liquid Dosages offers scientists and students the foundation and practical guidance to make and analyze semisolid and liquid formulations.

  • Unique coverage of the underlying chemistry that makes possible stable dosages
  • Quality content written by experienced experts from the drug development industry
  • Valuable information for academic and industrial scientists developing topical and liquid dosage formulations for pharmaceutical as well as skin care and cosmetic products


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18057

Essential Pharmacokinetics

A Primer for Pharmaceutical Scientists

 

Academic Press, 2015.

ISBNs 9780128014110

Colección: ScienceDirect

Resumen (en inglés): Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences.  This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceutical product development, and is useful as both a self-study and classroom resource.  Content coverage includes detailed discussions of common models and important pharmacokinetic concepts such as biological half-life, clearance, excretion, multiple dosage regimens and more.  Numerous equations, practical examples and figures are incorporated to clearly illustrate the theoretical background of pharmacokinetic behavior of drugs and excipients.

  • Shows how to apply basic pharmacokinetic methods to evaluate drugs, excipients and drug products
  • Uses guided practice questions, mathematical concepts and real-world examples for self-assessment and retention purposes
  • Illustrates how to write and evaluate drug registration files


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28947

Estudos de utilização de medicamentos

noções básicas

 

SciELO Books - Editora FIOCRUZ, 2000.

ISBNs 9788575412657

Colección: Directory of Open Access Books


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241

Ethnopharmacology of Medicinal Plants

Asia and the Pacific

 

13th ed. Totowa, NJ: Humana Press Inc., 2007.

ISBNs 9781588297488 9781597451604

Colección: SpringerLink


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