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Gran Área: Ciencias médicas y de la salud
Área: Medicina básica
Subárea: Farmacología y farmacia

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Resultado: 243 registro(s)

17442

Concepts and Models for Drug Permeability Studies

Cell and Tissue Based in Vitro Culture Models

 

Woodhead Publishing, 2015.

ISBNs 9780081000946

Colección: ScienceDirect

Resumen (en inglés):

This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route.

  • Updated information regarding the most recent in vitro models to study the permeability of drugs
  • Short and concise chapters covering all the biological barriers with interest in drug permeability
  • A combination of bibliographic information related with individual models and footnote instructions of technical procedures for construction of cell and tissue-based models
  • Simple and clear scientific content, adaptable for young scientists and experimented researchers


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23560

Contemporary Bioethics

Islamic Perspective

 

Springer, 2015.

ISBNs 9783319184272 9783319184289

Colección: Directory of Open Access Books


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17483

Controlled Drug Delivery

The Role of Self-Assembling Multi-task Excipients

 

Woodhead Publishing, 2015.

ISBNs 9781907568459

Colección: ScienceDirect

Resumen (en inglés): In complex macromolecules, minor modifications can generate major changes, due to self-assembling capacities of macromolecular or supramolecular networks. Controlled Drug Delivery highlights how the multifunctionality of several materials can be achieved and valorized for pharmaceutical and biopharmaceutical applications. Topics covered in this comprehensive book include: the concept of self-assembling; starch and derivatives as pharmaceutical excipients; and chitosan and derivatives as biomaterials and as pharmaceutical excipients. Later chapters discuss polyelectrolyte complexes as excipients for oral administration; and natural semi-synthetic and synthetic materials. Closing chapters cover protein-protein associative interactions and their involvement in bioformulations; self-assembling materials, implants and xenografts; and provide conclusions and perspectives.

  • Offers novel perspectives of a new concept: how minor alterations can induce major self-stabilization by cumulative forces exerted at short and long distances
  • Gives guidance on how to approach modifications of biopolymers for drug delivery systems and materials for implants
  • Describes structure-properties relationships in proposed excipients, drug delivery systems and biomedical materials


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22593

Corporate Data Quality

Voraussetzung erfolgreicher Geschäftsmodelle

 

Springer, 2016.

ISBNs 9783662468050 9783662468067

Colección: Directory of Open Access Books


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2710

Cytochrome P450

Structure, Mechanism, and Biochemistry

 

3rd ed. Boston, MA: Kluwer Academic/Plenum Publishers, 2005.

ISBNs 9780306483240 9780387274478

Colección: SpringerLink


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3752

Cytokines in the Genesis and Treatment of Cancer

 

13th ed. Totowa, NJ: Humana Press Inc., 2007.

Título de la serie/colección: Cancer Drug Discovery and Development.

ISBNs 9780896038202 9781597454551

Colección: SpringerLink


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17597

Delivery System Handbook for Personal Care and Cosmetic Products

Technology, Applications, and Formulations

 

William Andrew Publishing, 2005.

ISBNs 9780815515043

Colección: ScienceDirect

Resumen (en inglés): Novel delivery systems designed to facilitate the use of ôfountain of youthö and other functional actives is an idea whose time has come. In a rapidly growing global market eager for products that really work, accelerating market pull forces and technology push have set the stage for this foundation text. This ômust haveö book has been carefully designed for training, development and synergistic technology transfer across the personal care, cosmetic and pharmaceutical industries. It is not only intended for scientists and technologists but will also be of high interest to market development and business personnel. This book will cause a breakthrough in effective interaction among technology and marketing. It is a showcase for understanding, using and marketing the technology of why and how delivery systems work as well as current, emerging/potential applications and working formulations.

Each chapter is written by one or more experts in the field. A wide range of companies serving the global marketplace are represented. These companies offer numerous types of delivery systems containing highly desirable functional actives, delivery system technology development services, and opportunities for technology licensing, mergers and acquisitions.

A unique feature of the book is the use of Mind MapÖ technology to capture and present the essence of the thinking of over 80 authors in a ôBook-at-a-Glanceö Executive Overview section. This section has been specifically designed to empower decision making leading to the development of innovative product differentiation in a global context.


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17614

Design and Manufacture of Pharmaceutical Tablets

 

Academic Press, 2015.

ISBNs 9780128021828

Colección: ScienceDirect

Resumen (en inglés): Design and Manufacture of Pharmaceutical Tablets offers real world solutions and outcomes of formulation and processing challenges of pharmaceutical tablets.  This book includes numerous practical examples related to actual formulations that have been validated and marketed and covers important data in the areas of stability, dissolution, bioavailibity and processing.  It provides important background and theoretical information on design and manufacturing and includes a full section dedicated to design experimental methodology and statistics.  In addition, this book offers a a general discussion of excipients used in proper tablet design along with practical examples related to excipients.  Drug development scientists in industry and academia, as well as students in the pharmaceutical sciences will greatly benefit from the practical knowledge and case examples provided throughout this book.

  • Incorporates important mathematical models and computational applications
  • Includes unique content on central composite design and augmented simplex lattice
  • Provides background on important design principles with emphasis on quality-based design (QBD) of pharmaceutical dosage forms


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17680

Developments in Turbomachinery Flow

Forward Curved Centrifugal Fans

 

Woodhead Publishing, 2015.

ISBNs 9781782421924

Colección: ScienceDirect

Resumen (en inglés):

Developments in Turbomachinery Flow: Forward Curved Centrifugal Fans explores the forward curved squirrel cage fan as an excellent instrument for fluid mechanics research in turbomachines.

The book explores phenomena such as jet/wake interaction, circulation, separation and noise in turbomachines, also addressing the characteristics that are specific to this fan and applications in other centrifugal turbomachines.

Chapters begin with a general introduction that includes research techniques and a survey of older research, and then proceed into a detailed description of improvements for different parts of the fan, including the inlet, the rotor and the volute. Final sections include a comprehensive discussion on geometrical modifications that could improve performance without impacting cost.

  • Explores how forward curved centrifugal fans have wide industrial application
  • Discusses the strong trade-off between fan aerodynamics and construction cost
  • Provides a wide selection of optimums for geometrical configuration
  • Introduces new geometries that can improve performance and reduce noise for the same construction cost
  • Presents fluid phenomena as a potential research field for this fan


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6712

Drug and Biological Development

From Molecule to Product and Beyond

 

13th ed. Boston, MA: Springer Science+Business Media, 2007.

ISBNs 9780387329789 9780387690940

Colección: SpringerLink


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