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Gran Área: Ciencias médicas y de la salud
Área: Ciencias médicas y de la salud (general)
Subárea: Ciencias médicas y de la salud (general)

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Resultado: 540 registro(s)

17049

Biotechnology for Waste and Wastewater Treatment

 

William Andrew Publishing, 1997.

ISBNs 9780815514091

Colección: ScienceDirect

Resumen (en inglés): This book examines the practices used or considered for biological treatment of water/waste-water and hazardous wastes. The technologies described involve conventional treatment processes, their variations, as well as future technologies found in current research. The book is intended for those seeking an overview to the biotechnological aspects of pollution engineering, and covers the major topics in this field. The book is divided into five major sections and references are provided for those who wish to dig deeper.


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17082

Brain Lipids in Synaptic Function and Neurological Disease

Clues to Innovative Therapeutic Strategies for Brain Disorders

 

Academic Press, 2015.

ISBNs 9780128001110

Colección: ScienceDirect

Resumen (en inglés):

Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, brain lipids specifically interact with neurotransmitter receptors and control their activity. Moreover, brain lipids play a key role in the generation and neurotoxicity of amyloidogenic proteins involved in the pathophysiology of neurological diseases. The aim of this book is to provide for the first time a comprehensive overview of brain lipid structures, and to explain the roles of these lipids in synaptic function, and in neurodegenerative diseases, including Alzheimer’s, Creutzfeldt-Jakob’s and Parkinson’s. To conclude the book, the authors present new ideas that can drive innovative therapeutic strategies based on the knowledge of the role of lipids in brain disorders.

  • Written to provide a "hands-on" approach for readers
  • Biochemical structures explained with molecular models, and molecular mechanisms explained with simple drawings
  • Step-by-step guide to memorize and draw lipid structures
  • Each chapter features a content summary, up-to-date references for additional study, and a key experiment with an explanation of the technique


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17117

Building the Most Complex Structure on Earth

An Epigenetic Narrative of Development and Evolution of Animals

 

Elsevier, 2013.

ISBNs 9780124016675

Colección: ScienceDirect

Resumen (en inglés):

Building the Most Complex Structure on Earth provides readers with a basic biological education an easy and understandable introduction into a new epigenetic theory of development and evolution. This is a novel theory that describes the epigenetic mechanisms of the development and evolution of animals and explains the colossal evolution and diversification of animals from a new post-genetic perspective. Modern biology has demonstrated the existence of a common genetic toolkit in the animal kingdom, but neither the number of genes nor the evolution of new genes is responsible for the development and evolution of animals. The failure to understand how the same genetic toolkit is used to produce millions of widely different animal forms remains a perplexing conundrum in modern biology. The novel theory shows that the development and evolution of the animal kingdom are functions of epigenetic mechanisms, which are the competent users of the genetic toolkit.

  • Provides a comprehensive view of the epigenetic aspects of reproduction, development, and evolution.
  • Highly rigorous, but simple enough for readers with only a basic knowledge of biology.


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17132

Calculations for Molecular Biology and Biotechnology

A Guide to Mathematics in the Laboratory

 

2nd ed. Academic Press, 2011.

ISBNs 9780123756909

Colección: ScienceDirect

Resumen (en inglés): Calculations for Molecular Biology and Biotechnology: A Guide to Mathematics in the Laboratory, Second Edition, provides an introduction to the myriad of laboratory calculations used in molecular biology and biotechnology.
The book begins by discussing the use of scientific notation and metric prefixes, which require the use of exponents and an understanding of significant digits. It explains the mathematics involved in making solutions; the characteristics of cell growth; the multiplicity of infection; and the quantification of nucleic acids. It includes chapters that deal with the mathematics involved in the use of radioisotopes in nucleic acid research; the synthesis of oligonucleotides; the polymerase chain reaction (PCR) method; and the development of recombinant DNA technology. Protein quantification and the assessment of protein activity are also discussed, along with the centrifugation method and applications of PCR in forensics and paternity testing.

Key Features:
* Topics range from basic scientific notations to complex subjects like nucleic acid chemistry and recombinant DNA technology
* Each chapter includes a brief explanation of the concept and covers necessary definitions, theory and rationale for each type of calculation
* Recent applications of the procedures and computations in clinical, academic, industrial and basic research laboratories are cited throughout the text

New to this Edition:
* Updated and increased coverage of real time PCR and the mathematics used to measure gene expression
* More sample problems in every chapter for readers to practice concepts


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17133

Calculations for Molecular Biology and Biotechnology

 

3rd ed. Academic Press, 2016.

ISBNs 9780128022115

Colección: ScienceDirect

Resumen (en inglés):

Calculations in Molecular Biology and Biotechnology, Third Edition, helps researchers utilizing molecular biology and biotechnology techniques—from student to professional—understand which type of calculation to use and why. Research in biotechnology and molecular biology requires a vast amount of calculations. Results of one data set become the basis of the next. An error of choosing the wrong type of equation can turn what would have been a successful research project or weeks of labor and research into a veritable house of cards. It could be how you calculated the medium in which you test your sample to calculating how long it takes a sample to grow to calculating the synthesis of multiple variables.

In one easy to use reference, Stephenson reviews the mathematics and statistics related to the day-to-day functions of biotechnology and molecular biology labs, which is a sticking point for many students, technicians, and researchers. The book covers all of the basic mathematical and statistical needs for students and professionals, providing them with a useful tool for their work.

  • Features comprehensive calculations in biotechnology and molecular biology experiments from start to finish
  • Provides coverage ranging from basic scientific notations to complex subjects like nucleic acid chemistry and recombinant DNA technology
  • Includes recent applications of the procedures and computations in clinical, academic, industrial, and basic research laboratories cited throughout the text
  • Features new coverage of digital PCR and protein quantification including chromatography and radiolabelling of proteins
  • Includes more sample problems in every chapter for readers to practice concepts


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17138

Cancer Genomics

From Bench to Personalized Medicine

 

Academic Press, 2014.

ISBNs 9780123969675

Colección: ScienceDirect

Resumen (en inglés):

Cancer Genomics addresses how recent technological advances in genomics are shaping how we diagnose and treat cancer. Built on the historical context of cancer genetics over the past 30 years, the book provides a snapshot of the current issues and state-of-the-art technologies used in cancer genomics. Subsequent chapters highlight how these approaches have informed our understanding of hereditary cancer syndromes and the diagnosis, treatment and outcome in a variety of adult and pediatric solid tumors and hematologic malignancies. The dramatic increase in cancer genomics research and ever-increasing availability of genomic testing are not without significant ethical issues, which are addressed in the context of the return of research results and the legal considerations underlying the commercialization of genomic discoveries. Finally, the book concludes with "Future Directions", examining the next great challenges to face the field of cancer genomics, namely the contribution of non-coding RNAs to disease pathogenesis and the interaction of the human genome with the environment.

  • Tools such as sidebars, key concept summaries, a glossary, and acronym and abbreviation definitions make this book highly accessible to researchers from several fields associated with cancer genomics.
  • Contributions from thought leaders provide valuable historical perspective to relate the advances in the field to current technologies and literature.


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17140

Cancer Theranostics

 

Academic Press, 2014.

ISBNs 9780124077225

Colección: ScienceDirect

Resumen (en inglés): BMA Medical Book Awards 2015: Highly Commended, Oncology, British Medical Association

Aiding researchers seeking to eliminate multi-step procedures, reduce delays in treatment and ease patient care, Cancer Theranostics reviews, assesses, and makes pertinent clinical recommendations on the integration of comprehensive in vitro diagnostics, in vivo molecular imaging, and individualized treatments towards the personalization of cancer treatment.

Cancer Theranostics describes the identification of novel biomarkers to advance molecular diagnostics of cancer. The book encompasses new molecular imaging probes and techniques for early detection of cancer, and describes molecular imaging-guided cancer therapy. Discussion also includes nanoplatforms incorporating both cancer imaging and therapeutic components, as well as clinical translation and future perspectives.

  • Supports elimination of multi-step approaches and reduces delays in treatments through combinatorial diagnosis and therapy
  • Fully assesses cancer theranostics across the emergent field, with discussion of biomarkers, molecular imaging, imaging guided therapy, nanotechnology, and personalized medicine
  • Content bridges laboratory, clinic, and biotechnology industries to advance biomedical science and improve patient management


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17185

Cell Biology

Translational Impact in Cancer Biology and Bioinformatics

 

Academic Press, 2016.

ISBNs 9780128018538

Colección: ScienceDirect

Resumen (en inglés): Cell Biology: Translational Impact in Cancer Biology and Bioinformatics provides insight into the implications for cell cycle regulation and cell proliferation in cancer growth and dissemination. Offering guidance for techniques and tools to help with diagnosis, this publication provides users with a broad view of this research area, and is also useful for both early and experienced researchers across cell biology, cancer research, molecular biology, and in clinical and translational science.

  • Offers insight into how cell cycle and cell division relates to cancer biology
  • Emphasizes flow cytometry and other cell biology techniques for diagnosis
  • Includes recommendations for integration and analyzation of molecular and clinical data


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17198

Cell Physiology Source Book

Essentials of Membrane Biophysics

 

4th ed. Academic Press, 2011.

ISBNs 9780123877383

Colección: ScienceDirect

Resumen (en inglés): This authoritative book gathers together a broad range of ideas and topics that define the field. It provides clear, concise, and comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics. The 4e contains substantial new material. Most chapters have been thoroughly reworked. The book includes chapters on important topics such as sensory transduction, the physiology of protozoa and bacteria, and synaptic transmission.

  • Authored by leading researchers in the field
  • Clear, concise, and comprehensive coverage of all aspects of cellular physiology, from fundamental concepts to more advanced topics
  • Full color illustrations


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17203

Cellular Endocrinology in Health and Disease

 

Academic Press, 2014.

ISBNs 9780124081345

Colección: ScienceDirect

Resumen (en inglés):

Cellular Endocrinology in Health and Disease describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. Among these are those whose function was not obvious until recently, including the endocrine functions of bone and the adipose tissue.

Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and P. Michael Conn, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts. 

  • Covers systemic endocrine action at the cellular level in both health and disease
  • Delivers information on the integration of cell identity and endocrinology
  • Incorporates recent developments in endocrinology to provide an up-to-date reference to researchers


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