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Gran Área: Ciencias médicas y de la salud
Área: Ciencias médicas y de la salud (general)
Subárea: Ciencias médicas y de la salud (general)

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Resultado: 540 registro(s)

7903

Acceleration and Improvement of Protein Identification by Mass Spectrometry

 

13th ed. Dordrecht: Springer, 2005.

ISBNs 9781402033186 9781402033193

Colección: SpringerLink


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22962

Acute-Care Nurse Practitioner, The

A Transformational Journey

 

Athabasca University Press, 2013.

ISBNs 9781927356265 9781927356272 9781927356289

Colección: Directory of Open Access Books

Resumen (en inglés): From the moment it was first proposed, the role of the nurse practitioner has been steeped in controversy. In the fields of both nursing and medicine, the idea that a nurse practitioner can, to some degree, serve as a replacement for the physician has sparked heated debates. Perhaps for that reason, despite the progress of the nurse practitioner movement, NPs have been reluctant to speak about themselves and their work, and their own vision of their role has thus remained largely invisible. Current research is dominated by instrumental and economic modes of discourse and tends to focus on the clinical activities associated with the role. Although information about demographics, educational preparation, position titles, reporting relationships, and costs of care contribute to our understanding, what was missing was an exploration of the lived experience of the nurse practitioner, as a means to deepen that understanding as well as our appreciation for their role.


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16551

Adenoviral Vectors for Gene Therapy

 

2nd ed. Academic Press, 2016.

ISBNs 9780128002766

Colección: ScienceDirect

Resumen (en inglés):

Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research.

This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors.

  • Provides complete coverage of the basic biology of adenoviruses, as well as their construction, propagation, and purification of adenoviral vectors
  • Introduces common strategies for the development of adenoviral vectors, along with cutting-edge methods for their improvement
  • Demonstrates noninvasive imaging of adenovirus-mediated gene transfer
  • Discusses utility of adenoviral vectors in animal disease models
  • Considers Federal Drug Administration regulations for human clinical trials


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16583

Advanced Mechanical Models of DNA Elasticity

 

Academic Press, 2016.

ISBNs 9780128019993

Colección: ScienceDirect

Resumen (en inglés):

Advanced Mechanical Models of DNA Elasticity includes coverage on 17 different DNA models and the role of elasticity in biological functions with extensive references. The novel advanced helicoidal model described reflects the direct connection between the molecule helix structure and its specific properties, including nonlinear features and transitions. It provides an introduction to the state of the field of DNA mechanics, known and widely used models with their short analysis, as well as coverage on experimental methods and data, the influence of electrical, magnetic, ionic conditions on the persistence length, and dynamics with viscosity influence. It then addresses the need to understand the nature of the non-linear overstretching transition of DNA under force and why DNA has a negative twist-stretch coupling.

  • Includes coverage of 17 contemporary models of DNA mechanics with analysis
  • Provides comparison of DNA and RNA mechanical features
  • Covers advances in experimental techniques including AFM, X-ray, and optical tweezers
  • Contains extensive references for further reading


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16640

Advances in Smart Medical Textiles

Treatments and Health Monitoring

 

Woodhead Publishing, 2016.

ISBNs 9781782423799

Colección: ScienceDirect

Resumen (en inglés):

Advances in Smart Medical Textiles: Treatments and Health Monitoring provides comprehensive coverage on smart textiles, the emerging and important materials that are finding applications in the fields of medicine and healthcare.

The book explores the range of smart textiles available for use in medicine and the transfer of these innovative technologies into medical applications. Early chapters survey various smart fibers, fabrics, and finishes, while subsequent sections focus on the role of smart textiles in treating patients, from wound care to rehabilitation, and the use of textile-based sensors and wearable electronics for monitoring patient health.

  • Provides a comprehensive review of the materials used in smart medical textiles
  • Analyzes the application of these textiles in medical treatments and sensors for health monitoring
  • Covers the range of international research in the field and keeps focus on the needs of the textile industry


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16673

Alcohol and Its Biomarkers

Clinical Aspects and Laboratory Determination

 

Elsevier, 2015.

ISBNs 9780128003398

Colección: ScienceDirect

Resumen (en inglés):

Alcohol and Its Biomarkers: Clinical Aspects and Laboratory Determination is a concise guide to all currently known alcohol biomarkers, their clinical application, and the laboratory methods used to detect them. Pathologists can use this resource to understand the limitations and cost factors associated with each method for determining certain alcohol biomarkers. In addition, interferences in these determinations are discussed, so that clinicians can understand the causes of falsely elevated biomarkers and pathologists and laboratory scientists can potentially eliminate them. The book focuses on the analytical methods used to detect alcohol in blood and urine, the limitations of alcohol determination using enzymatic methods, and the differences between clinical and forensic alcohol measurement. Chapters also cover cutting-edge alcohol biomarkers for potential use.

  • Focuses on the analytical methods used for detecting alcohol in blood and urine along with the pitfalls and limitations of alcohol determination using enzymatic methods
  • Explains the difference between clinical and forensic alcohol measurement
  • Includes a brief overview of the benefits of consuming alcohol in moderation and the hazards of heavy drinking


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16682

Allergy, Immunity and Tolerance in Early Childhood

The First Steps of the Atopic March

 

Academic Press, 2016.

ISBNs 9780124202269

Colección: ScienceDirect

Resumen (en inglés):

Allergy, Immunity and Tolerance in Early Childhood: The First Steps of the Atopic March provides valuable insights on the atopic diseases, including asthma, allergic rhinitis, atopic dermatitis, and food allergies, which have developed into major health problems in most parts of the world.

As the natural history of these chronic diseases has been extensively studied, including their major genetic, environmental, and lifestyle determinants and potential protective factors, the book presents tactics on how pediatric allergists can provide early intervention. In addition, the book unites key, global experts in the field who summarize their collective, and current, knowledge of the early stage of the "Atopic March", along with novel ideas for potential options of prevention.

  • Summarizes the current knowledge of the epidemiological, genetic, and cellular basis of allergic diseases
  • Ideal reference for the study of allergies in young children, atopic dermatitis, allergic rhinitis, childhood asthma, and food allergies
  • Provides landmark findings in the field of immunology and allergy development
  • Fulfills the need for a book that focuses on primary and secondary allergy prevention, especially during the first years of life
  • Unites key, global experts in the field who summarize their collective, and current, knowledge, along with novel ideas for potential options of prevention


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16693

Amphioxus Immunity

Tracing the Origins of Human Immunity

 

Academic Press, 2016.

ISBNs 9780128499030

Colección: ScienceDirect

Resumen (en inglés):

Amphioxus Immunity: Tracing the Origin of Human Immunity covers a remarkable range of information about Amphioxus and its evolutionary context. This compilation of what is currently known about Amphioxus, with a sharp focus on its immune system, includes 13 topics, such as:

  • Amphioxus as a model for understanding the evolution of vertebrates
  • basic knowledge of immunology
  • immune organs and cells of amphioxus
  • a genomic and transcriptomic view of the Amphioxus immunity
  • pattern recognition system in Amphioxus
  • transcription factors in Amphioxus
  • the complement system of Amphioxus
  • the oxidative burst system in Amphioxus
  • immune effectors in Amphioxus
  • lipid signaling of immune response in Amphioxus
  • apoptosis in amphioxus; primitive adaptive immune system of Amphioxus
  • and future research directions

This valuable reference book is loaded with information that will be useful for anyone who wishes to learn more about the origin of vertebrates and adaptive immunity.

  • Provides new evidence on the origin of the adaptive immune system, the evolution of innate immunity, and evolution-stage specific immune defense mechanisms
  • Not only presents the cells and molecules involved in the adaptive immune response in Amphioxus, but also characterizes the origination and evolution of the gene families and pathways involved in innate immunity
  • Includes much pioneering work, from the molecular, genomic, and cellular to the individual level


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16714

Anaerobiosis and Stemness

An evolutionary paradigm

 

Academic Press, 2016.

ISBNs 9780128005408

Colección: ScienceDirect

Resumen (en inglés):

Anaerobiosis and Stemness: An evolutionary paradigm provides a context for understanding the many complexities and evolutionary features of stem cells and the clinical implications of anaerobiosis stem cells.  Combining theoretical and experimental knowledge, the authors provide a broad understanding of how the absence or low concentration of oxygen can play an influential role in the maintenance and self-renewal of stem cells and stem cell differentiation.  This understanding has clinical implications for the fields of regenerative medicine, cancer biology and transplantation, as well as cell engineering and cell therapy. Anaerobiosis and Stemness is an important resource for stem cell and developmental biologists alike, as well as oncologists, cancer biologists, and researchers using stem cells for regeneration.

  • Highlights the molecular and evolutionary features of stem cells which make them so important to all biological research
  • Explores methods of isolation, characterization, activation, and maintenance of stem cells
  • Includes models for clinical application in regenerative medicine, cancer therapy, and transplantation


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16716

Analysis of Complex Disease Association Studies

A Practical Guide

 

Academic Press, 2011.

ISBNs 9780123751423

Colección: ScienceDirect

Resumen (en inglés): According to the National Institute of Health, a genome-wide association study is defined as any study of genetic variation across the entire human genome that is designed to identify genetic associations with observable traits (such as blood pressure or weight), or the presence or absence of a disease or condition. Whole genome information, when combined with clinical and other phenotype data, offers the potential for increased understanding of basic biological processes affecting human health, improvement in the prediction of disease and patient care, and ultimately the realization of the promise of personalized medicine. In addition, rapid advances in understanding the patterns of human genetic variation and maturing high-throughput, cost-effective methods for genotyping are providing powerful research tools for identifying genetic variants that contribute to health and disease. (good paragraph)

This burgeoning science merges the principles of statistics and genetics studies to make sense of the vast amounts of information available with the mapping of genomes. In order to make the most of the information available, statistical tools must be tailored and translated for the analytical issues which are original to large-scale association studies. This book will provide researchers with advanced biological knowledge who are entering the field of genome-wide association studies with the groundwork to apply statistical analysis tools appropriately and effectively. With the use of consistent examples throughout the work, chapters will provide readers with best practice for getting started (design), analyzing, and interpreting data according to their research interests. Frequently used tests will be highlighted and a critical analysis of the advantages and disadvantage complimented by case studies for each will provide readers with the information they need to make the right choice for their research. Additional tools including links to analysis tools, tutorials, and references will be available electronically to ensure the latest information is available.

* Easy access to key information including advantages and disadvantage of tests for particular applications, identification of databases, languages and their capabilities, data management risks, frequently used tests
* Extensive list of references including links to tutorial websites
* Case studies and Tips and Tricks


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