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Gran Área: Ciencias exactas y naturales
Área: Ciencias biológicas
Subárea: Bioquímica

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Resultado: 424 registro(s)

6760

Class 2 · Transferases VI

EC 2.4.2.1-2.5.1.30 Vol. 33

 

2nd ed. Berlin, Heidelberg: Springer-Verlag, 2007.

Título de la serie/colección: Springer Handbook of Enzymes.

ISBNs 9783540325888 9783540497530

Colección: SpringerLink


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8007

Class 2 · Transferases VI

EC 2.5.1.31-2.6.1.57 Vol. 34

 

2nd ed. Berlin, Heidelberg: Springer-Verlag, 2007.

Título de la serie/colección: Springer Handbook of Enzymes.

ISBNs 9783540365099 9783540497554

Colección: SpringerLink


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17315

Clinical Challenges in Therapeutic Drug Monitoring

Special Populations, Physiological Conditions and Pharmacogenomics

 

Elsevier, 2016.

ISBNs 9780128020258

Colección: ScienceDirect

Resumen (en inglés):

Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring.

This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process of therapeutic drug monitoring for individual dosage adjustment and avoiding drug toxicity for certain drugs within a narrow therapeutic window. The book is written specifically for busy clinicians, fellows, and trainees who order therapeutic drug monitoring and need to get more familiar with testing methodologies, issues of interferences, and interpretation of results in certain patient populations.

  • Offers busy clinicians, pathologists, and trainees a concise resource on the key aspects and critical issues in therapeutic drug monitoring
  • Focuses on patient populations such as infants and children, pregnant women, elderly patients, and obese patients, who have special requirements in therapeutic drug monitoring
  • Explores special topics in therapeutic drug monitoring including free drug monitoring and common immunoassay interference
  • Explains how individual dosage adjustments can prevent drug toxicity for certain drugs within a narrow therapeutic window


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17323

Clinical Genomics

 

Academic Press, 2015.

ISBNs 9780124047488

Colección: ScienceDirect

Resumen (en inglés):

Clinical Genomics provides an overview of the various next-generation sequencing (NGS) technologies that are currently used in clinical diagnostic laboratories. It presents key bioinformatic challenges and the solutions that must be addressed by clinical genomicists and genomic pathologists, such as specific pipelines for identification of the full range of variants that are clinically important.

This book is also focused on the challenges of diagnostic interpretation of NGS results in a clinical setting. Its final sections are devoted to the emerging regulatory issues that will govern clinical use of NGS, and reimbursement paradigms that will affect the way in which laboratory professionals get paid for the testing.

  • Simplifies complexities of NGS technologies for rapid education of clinical genomicists and genomic pathologists towards genomic medicine paradigm
  • Tried and tested practice-based analysis for precision diagnosis and treatment plans
  • Specific pipelines and meta-analysis for full range of clinically important variants


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6597

Combinatorial Chemistry on Solid Supports

Vol. 278

 

13th ed. Berlin, Heidelberg: Springer-Verlag GmbH, 2007.

Título de la serie/colección: Topics in Current Chemistry. ISSN 0340-1022,

ISBNs 9783540725091 9783540725107

Colección: SpringerLink


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5207

Combined and Hybrid Adsorbents

Fundamentals and Applications

 

13th ed. Dordrecht: Springer, 2006.

Título de la serie/colección: NATO Security through Science Series.

ISBNs 9781402051708 9781402051722

Colección: SpringerLink


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7131

Communication in Plants

Neuronal Aspects of Plant Life

 

13th ed. Berlin, Heidelberg: Springer, 2006.

ISBNs 9783540284758 9783540285168

Colección: SpringerLink


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3376

Comparative Genomics

Using Fungi as Models Vol. 15

 

13th ed. Berlin, Heidelberg: Springer-Verlag GmbH, 2006.

Título de la serie/colección: Topics in Current Genetics. ISSN 1610-2096,

ISBNs 9783540314806 9783540314950

Colección: SpringerLink


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2947

Complex Intracellular Structures in Prokaryotes

Vol. 2

 

13th ed. Berlin, Heidelberg: Springer-Verlag, 2006.

Título de la serie/colección: Microbiology Monographs. ISSN 1862-5576,

ISBNs 9783540325246 9783540325260

Colección: SpringerLink


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21205

Comprehensive Sourcebook of Bacterial Protein Toxins, The

 

4th ed. Academic Press, 2015.

ISBNs 9780128001882

Colección: ScienceDirect

Resumen (en inglés):

The Comprehensive Sourcebook of Bacterial Protein Toxins 4th Edition, contains chapters written by internationally known and well-respected specialists. This book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins. Considerable progress has been made in understanding the structure, function, interaction and trafficking into cells, as well as mechanism of action of toxins. Bacterial toxins are involved in the pathogenesis of many bacteria, some of which are responsible for severe diseases in human and animals, but can also be used as tools in cell biology to dissect cellular processes or used as therapeutic agents. Novel recombinant toxins are already proposed in the treatment of some diseases, as well as new vaccines. Alternatively, certain toxins are also considered as biological weapons or bioterrorism threats. Given the multifaceted aspects of toxin research and the multidisciplinary approaches adopted, toxins are of great interest in many scientific areas from microbiology, virology, cell biology to biochemistry and protein structure. This new edition is written with a multidisciplinary audience in mind and contains 5 new chapters that reflect the latest research in this area. Other chapters have been combined, deleted and fully revised as necessary to deliver relevant and valuable content.

  • Descriptions of relevant toxins as well as representative toxins of the main bacterial toxin families to allow for a better comparison between them.
  • Focused chapters on toxin applications and common properties or general features of toxins.


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